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In turn, in the VPA-induced rodent model of ASD, 4-week treatment with risperidone at both tested doses (1 and 3 mg/kg) increased Adar2 relative gene expression and decreased GluA2 Q:R ratio in the hippocampus and the PFC

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Key points The procedure covers the design and preparation of the nanoframeworks, the loading of functional nucleic acid sequences via hybridization chain reaction and their characterization, followed by their evaluation as therapeutics and as biosensors

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doi: 10.1186/s12974-020-01845-x, 142 SunW.WenM.LiuM.WangQ.LiuQ.LiL.et al

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